Zantac (ranitidine) is a h2 antagonist. Below: how 4 show and racing governing bodies list it, every published detection time for the dose and route studied, and the document and page each value comes from.HISA: Controlled medicationnamed in the rules of 22 state racing commissions
None of the detection-time lists we carry (FEI, HIWU, IFHA/EHSLC, Equestrian Canada, USEF) publishes a detection time for Zantac. ShowSafe Pro answers "Unknown" for it, never "Clear", and quotes what each rulebook says about unlisted substances.
The Racing Medication and Testing Consortium publishes withdrawal guidance built on HISA's detection times. It is advisory, not a rule, and ShowSafe Pro shows it beside the HISA result, never in place of it.
| Dose and route | Withdrawal guidance | HISA detection time | Source |
|---|---|---|---|
| 8 mg/kg orally twice daily for 7 doses · oral | 24 h (1 day) | 24 h (1 day) | RMTC advisory p. 4 |
Transcribed from the governing bodies' own documents. Each entry links to the document and quotes the row it came from.
“c. the anti-ulcer medications: cimetidine, ranitidine, sucralfate or omeprazole.” — source p. 6
“13. Omeprazole/Ranitidine” — source p. 79
“Ranitidine ... 8 mg/kg orally twice daily for 7 doses ... RAT: 24 hours (9) ... 40 ng/mL in serum or plasma” — source p. 4
“Ranitidine ... Restricted administration time: 24 hours. 8 mg/kg orally twice daily for 7 doses. (9 horses) ... 40 ng/mL in serum or plasma” — source p. 26
“(b) The following may be administered up to 24 hours prior to Post-Time: ... (3) anti-ulcer medications (e.g., Cimetidine, Omeprazole, and Ranitidine);” — source p. 3
“Ranitidine Zantac 5 D” — source p. 50
“Ranitidine | 40 nanograms per milliliter of plasma or serum | 24 hours” — source p. 6
Zantac is named in the medication rules, threshold schedules or withdrawal guidance of 22 state racing commissions: Arizona, California, Colorado, Idaho, Illinois, Indiana, Kentucky, Louisiana, Maine, Maryland, Minnesota, Nebraska, New Jersey, New York, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Texas, Washington, West Virginia. Most states publish thresholds (concentrations), not times, and several adopt the ARCI schedule by reference. ShowSafe Pro Racing layers each state's rules over HISA or ARCI the way that state applies them, for all 32 states with live pari-mutuel racing.
A published detection time tells you how long Zantac stayed detectable in a handful of horses given one dose by one route. It does not tell you when your horse is clear: a bigger dose, a different route, repeated doses, a joint injection or a slower horse all push the real figure out, and every governing body says to add a safety margin set by your veterinarian. Here is how to read the rulebook.
ShowSafe Pro takes the doses already logged for your horse, matches each one to the published row for that dose and route, adds the margin your vet set, and flags anything the studies never covered as Unknown, ask your vet instead of guessing. Every answer shows the document, page and line it came from, for every rulebook the show runs under.
No. It is the approximate time Zantac stayed detectable in the horses studied, at that dose and route. Your horse, dose, route and number of doses may differ. Every governing body tells you to add a safety margin set by your veterinarian, and none publishes a withdrawal time. ShowSafe Pro applies the published row for the dose and route you actually gave, adds your vet's margin, and says 'Unknown' when the studies do not cover what you gave.